NS NS 5163 Heritable Neurological Diseases of Mice and Men

Many diseases of the mammalian nervous system are the result of mutations in single or multiple genes. In this course, we will explore the major inherited neurological disorders involving sensory, motor, and higher integrative systems. Our primary focus will be diseases of humans, but we will also consider insights gained in mouse, fly, and worm model systems. This course will have a molecular orientation with the goal of correlating the neurological phenotypes with the functions of the affected proteins. Experts on the various topics will present lectures, followed by student presentations of relevant literature.