CAN 5152 CANCER BIOLOGY I
Tumorigenesis is a multi-step process driven by genetic and epigenetic changes that occur over time. Although cancer is a heterogeneous disease, many human tumors exhibit similar acquired physiological features, defined as ¿The Hallmarks of Cancer¿ by Hanahan and Weinberg. This course will cover the underlying molecular and cellular biology involved in carcinogenesis, tumor growth, and metastasis. The implications of the biological findings on cancer prevention, diagnosis, and treatment will be covered.
The goal is course is to provide the student with a solid background in general cancer biology. Upon completion of the class, students should have basic understanding of the mechanisms by which tumors gain and maintain a growth advantage as well as potential therapeutic targets.